SUBUNIT HETEROGENEITY IN HUMAN SERUM BETA LIPOPROTEIN
نویسندگان
چکیده
منابع مشابه
Subunit heterogeneity in human serum beta lipoprotein.
The apoprotein of human serum beta lipoprotein has been prepared in a lipid-free and soluble form by a technique of interfacial extraction in the presence of guanidinium hydrochloride and nonionic amphiphile. Gel permeation chromatography of maleylated apobeta lipoprotein separates two protein fractions with different amino acid compositions. The smaller particle has a molecular weight of 2.6 x...
متن کاملActivation of lipoprotein lipase by lipoprotein fractions of human serum.
Triglycerides in fat emulsions are hydrolyzed by lipoprotein lipase only when they are "activated" by serum lipoproteins. The contribution of different lipoprotein fractions to hydrolysis of triglycerides in soybean oil emulsion was assessed by determining the quantity of lipoprotein fraction required to give half-maximal hydrolysis. Most of the activator property of whole serum from normolipid...
متن کاملRadioimmunoassay of beta lipoprotein-protein of rat serum.
A double antibody radioimmunoassay for rat serum beta lipoprotein-protein (beta Lp-protein) is described. The protein was purified by ultracentrifugation, selective heparin-manganous precipitation, and gel filtration on Sephadex G-200. Antiserum was prepared in rabbits by biweekly immunization and absorbed with nonbeta lipoprotein containing rat serum. Iodination with (125)I and purification by...
متن کاملProteolysis of Human Serum P-Lipoprotein*
It has been well known for some time that many native prot.cins arc attacked only extremely slowly by proteolytic enzymes, or often not at all (l-6). The seeming resistance of human serum lipoproteins toward proteolysis therefore appeared to be a common phenomenon. Recently, interactions between P-lipoproteins and polyanions, in particular amylopectin sulfate, have been studied (7, 8), and this...
متن کامل[Metastatic tumor of spermatic cord with elevation of serum human chorionic gonadotropin beta-subunit].
A 62-year-old man was presented with a firm mass in right scrotum. Serum LDH and AFP were within normal range, but hCG-beta was elevated (2.3 ng/ml). Under the diagnosis of right testicular tumor, he underwent right radical orchiectomy. The specimen was a spermatic cord tumor with poorly differentiated adenocarcinoma. hCG-beta was still elevated postoperatively and gastric fiber revealed adenoc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1970
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.66.4.1075